KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPI1
All Species:
47.88
Human Site:
Y48
Identified Species:
70.22
UniProt:
P60174
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60174
NP_000356.1
249
26669
Y48
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
P15426
249
26692
Y48
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
Dog
Lupus familis
XP_534904
249
26696
Y48
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
P17751
249
26694
Y48
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
Rat
Rattus norvegicus
P48500
249
26830
Y48
V
C
A
P
P
T
A
Y
I
D
F
A
R
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P00940
248
26602
Y47
V
C
G
A
P
S
I
Y
L
D
F
A
R
Q
K
Frog
Xenopus laevis
Q7ZWN5
248
26743
Y47
V
C
G
A
P
A
I
Y
L
D
F
A
R
Q
K
Zebra Danio
Brachydanio rerio
Q90XG0
248
26809
Y47
V
C
G
A
P
T
I
Y
L
D
Y
A
R
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29613
247
26607
Y46
V
I
G
C
P
A
I
Y
L
M
Y
A
R
N
L
Honey Bee
Apis mellifera
NP_001090623
247
26880
Y46
V
V
G
V
P
S
I
Y
L
T
Y
A
K
N
I
Nematode Worm
Caenorhab. elegans
Q10657
247
26556
Y46
V
V
A
P
P
A
P
Y
L
A
Y
A
K
S
K
Sea Urchin
Strong. purpuratus
NP_001116981
250
26829
Y48
V
V
A
P
P
T
V
Y
L
D
Y
M
N
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P12863
253
27006
Y46
E
V
V
V
S
P
P
Y
V
F
L
P
V
V
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKP6
315
33327
Y107
V
V
S
P
P
F
V
Y
I
D
Q
V
K
S
S
Baker's Yeast
Sacchar. cerevisiae
P00942
248
26777
Y46
V
I
C
P
P
A
T
Y
L
D
Y
S
V
S
L
Red Bread Mold
Neurospora crassa
Q7S2Z9
248
27215
Y46
V
I
A
P
P
A
L
Y
L
D
F
V
K
Q
N
Conservation
Percent
Protein Identity:
100
N.A.
99.1
98.3
N.A.
95.9
94.3
N.A.
N.A.
89.5
83.5
82.7
N.A.
64.2
63
61.8
63.2
Protein Similarity:
100
N.A.
100
99.1
N.A.
97.5
96.3
N.A.
N.A.
91.9
91.5
87.9
N.A.
75
76.3
73.4
76
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
66.6
66.6
60
N.A.
33.3
26.6
46.6
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
80
73.3
73.3
N.A.
46.6
53.3
66.6
66.6
Percent
Protein Identity:
N.A.
62
N.A.
50.1
53.4
57.8
Protein Similarity:
N.A.
75.1
N.A.
58.7
67.8
69.4
P-Site Identity:
N.A.
13.3
N.A.
40
33.3
53.3
P-Site Similarity:
N.A.
20
N.A.
53.3
53.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
19
0
32
32
0
0
7
0
69
0
0
0
% A
% Cys:
0
50
7
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
7
50
0
0
0
0
% F
% Gly:
0
0
32
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
0
0
0
32
0
38
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
69
% K
% Leu:
0
0
0
0
0
0
7
0
57
0
7
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
13
7
% N
% Pro:
0
0
0
63
94
7
13
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
50
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
57
0
0
% R
% Ser:
0
0
7
0
7
13
0
0
0
0
0
7
0
32
7
% S
% Thr:
0
0
0
0
0
44
7
0
0
7
0
0
0
0
0
% T
% Val:
94
32
7
13
0
0
13
0
7
0
0
13
13
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
38
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _